The Union University School of Nursing offers its program leading to the Bachelor of Science in Nursing (Basic BSN track and RN to BSN track). The RN to BSN track for Registered Nurses is offered on both the Jackson and Germantown Campuses. The program is approved by the Tennessee Board of Nursing and accredited by the Commission on Collegiate Nursing Education. CCNE may be contacted at One Dupont Circle, NW Suite 530, Washington, DC 20036-1120 or 202-887-6791.

The School of Nursing encourages the educational mobility of registered nurses holding the associate degree or diploma in nursing. All registered nurse students take NUR 333 upon entering the B.S.N. program. Upon successful completion of NUR 333, the student is awarded 37 hours of Nursing credit.

The University shares articulation agreements with area colleges (Jackson State Community College, Dyersburg State Community College, Northeast Mississippi Community College, Northwest Mississippi Community College, Southwest Tennessee Community College, University of Memphis) for the purpose of accommodating the learning needs of students while minimizing the repetition of non-nursing learning experiences.

RN to BSN students are strongly encouraged to hold membership in the Tennessee Nurses Association (TNA).